Therapeutic Interaction Features of AI Chatbots in Depression: A Systematic Review of Clinical Effectiveness and Design
A JMIR systematic review synthesizes clinical trials of AI-driven chatbots for depression, finding small-to-moderate symptom improvements versus controls that lose statistical significance under more conservative analysis. The paper concludes that while chatbots are promising and often acceptable to users, heterogeneous study designs and limited data mean their clinical value and best-practice design features remain uncertain.
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